CALCIUM-DEPENDENT PHOSPHOLIPASE A2 LEVELS IN ATTENTION DEFICIT HYPERACTIVITY DISORDER
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CALCIUM-DEPENDENT PHOSPHOLIPASE A2 LEVELS IN ATTENTION DEFICIT HYPERACTIVITY DISORDER

Turk J Child Adolesc Ment Health 2004;11(1):11-15
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Abstract

Objective:

Several previous studies indicated that some physical symptoms reported in Attention Deficit Hyperactivity Disorder (ADHD) are similar to symptoms in animals and humans deprived of essential fatty acids. Thus, phospholipid metabolism may play a role in the pathogenesis and clinical presentation of ADHD.

Method:

The serum activity of secretory calcium-dependent phospholipase A2 (sPLAJ in 39 boys with ADHD was compared with 18 age, sex and socioeconomic status matched normal controls.

Results:

There was no statistically significant difference between the mean sPLA2 activity levels of boys with ADHD and normal controls.

Discussion:

This study suggested that ADHD may not associated with dysfunction of PLA2-

Keywords: Attention deficit hyperactivity disorder, phospholipase A2, phospholipids